Light drinking linked to increased breast cancer risk

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Drinking as few as three to six glasses of wine per anniversary may access a woman's lifetime accident of breast blight by 15%, according to an assay by Harvard researchers.

The study, appear Tuesday in the Journal of the American Medical Assn., reaffirms that abundant booze use raises breast blight risk, and it adds that ablaze drinking matters too.
 
"Alcohol is a real risk factor, and the more you drink the higher your risk," said Dr. Steven A. Narod, the Canada research chair in breast cancer at the University of Toronto, who wrote a commentary accompanying the study.

Whether women should consider abstaining from even light alcohol consumption, however, is not easily answered, preventive health experts said.

On average, a U.S. woman's baseline risk of breast cancer is 1 in 8 over her lifetime, according to the American Cancer Society. The 15% increased risk that was linked to consumption of 5 to 9.9 grams of alcohol per day is modest, similar to the heightened risk associated with using estrogen-progesterone hormone therapy to treat symptoms of menopause. But it's far smaller than the fivefold increased risk that comes from inheriting certain mutations in the BRCA1 and BRCA2 genes.

Moreover, having a few drinks a week has been found to lower the incidence of heart disease by 25% to 40%. The average woman's lifetime risk for heart disease is 1 in 2.

The breast cancer findings were based on data from 105,986 women in the long-running Nurses' Health Study. Participants were assessed at regular intervals from 1980 until 2008 to record alcohol intake and cases of invasive breast cancer, among other things.

The abstraction does not prove that booze burning makes women added affected to breast cancer. But the advisers were able to abstract the articulation amid bubbler and breast blight by authoritative for a host of added accident factors, such as ancestors history of the ache and age at aboriginal pregnancy.

As in antecedent studies, the assay begin that women who captivated at atomic 30 grams of booze per day — about two drinks — were 51% added acceptable to advance breast blight than women who didn't booze at all. But for the aboriginal time, advisers were able to see that the accident of breast blight begins to acceleration with alike bashful booze intake."When you attending at this, you see a dose-response effect," said Dr. Wendy Y. Chen, the advance columnist of the cardboard and an abettor assistant of anesthetic at Brigham and Women's Hospital and Harvard Medical School in Boston. "That strengthens the actuality that what you're award is real."

Chen and her colleagues additionally approved that affair drinking, authentic as six or added drinks in one sitting, was associated with a 33% access in blight accident absolute of absolute booze assimilation over time and that booze burning amid the ages of 18 and 40 was affiliated with college breast blight accident afterwards in activity no amount what a woman's bubbler habits were afterwards age 40.The abstraction focused alone on alcohol's aftereffect on cancer-free women. It's cryptic what admonition about bubbler ability be accustomed to women who accept been diagnosed with cancer.

Hormones apparently comedy a key role in the alcohol-breast blight relationship, Chen said, because booze assimilation increases levels of the hormone estrogen, which is accepted to ammunition breast blight growth.

But bashful booze burning additionally raises HDL, the acceptable cholesterol, and added substances that advance affection health. The cardiovascular allowances apparently abate a baby added accident of breast cancer, said Dr. Tim Byers, accessory administrator for blight blockage and ascendancy at the University of Colorado Blight Center.
"The accommodation makes it actual difficult for women to apperceive what to do," he said. "There are not abounding examples of area there is accommodation for affection ache and breast cancer. Most of the risks for affection ache and breast blight are the same."

Considering that added women advance affection ache than breast cancer, Byers said, "it's reasonable" for women at boilerplate accident for both altitude to booze at low to abstinent levels. "But for women at college accident of breast blight it becomes a added difficult decision," he said. "The advisable affair for them may be to abstain alcohol."

Chen said she doesn't acquaint her patients to stop bubbler but to absolute assimilation to a few drinks a week.


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1 comments:

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